Demo
Genomics-aware CDS recommendations
Pick a synthetic sample to see how Engine 2's deterministic rule engine produces structured Recommendations from a parsed NGS report. Every output ships with a full evidence chain and a Non-Device CDS attestation.
How this view works
Recommendations are derived from the evidence-join endpoint: FDA-approved therapies become therapy-match cards, resistance-tagged CIViC evidence becomes resistance-warning cards, CPIC guidelines become PGx-dosing cards, ClinicalTrials.gov matches become trial-match cards. Engine 2 in production adds deterministic rule-engine logic for contraindications and combined-predicate triggers (e.g. BRCA + HRD → PARP) beyond what's rendered here.
How the CDS layer works under the hood
Deterministic rule routing across five categories — biomarker eligibility, drug-gene PGx, trial matching, contraindications, follow-up. Read full case walkthroughs: