Demo

Variant evidence lookup

Aggregated across CIViC, ClinVar, ClinicalTrials.gov, openFDA, and CPIC. Tier per Li et al. (2017) framework, paraphrased.

Reference data only, not for clinical use. UNMIRI is not a medical device. Do not paste patient identifiers.
Try an example

Try a worked example:

EGFR L858R · lung adenocarcinoma
Textbook positive. FDA-approved CDx plus active trials.
BRAF V600E · melanoma
BRAF/MEK combo evidence, vemurafenib lineage.
BRCA1 · ovarian cancer
PARP inhibitor pathway, ACMG/AMP framework.